Tumour targeting of lipid nanocapsules grafted with cRGD peptides
نویسندگان
چکیده
منابع مشابه
Tumour targeting of lipid nanocapsules grafted with cRGD peptides.
Combining targeting to therapy remains a major challenge in cancer treatment. To address this subject, the surface of lipid nanocapsules (LNC) was modified by grafting cRGD peptides, which are known to be recognised by αvβ3 integrins expressed by tumour endothelium and cancer cells. Applicability of this LNC-cRGD in tumour targeting was first assessed in vitro by the use of U87MG glioma cells. ...
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ژورنال
عنوان ژورنال: European Journal of Pharmaceutics and Biopharmaceutics
سال: 2014
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2013.12.006